GENETIC VARIABILITY OF THE CRYPTOSPORIDIUM GENUS
The study of genetic variability among the members of the Cryptosporidium genus isolated during any spontaneous infection
Currently, 41 valid species and several dozen genotypes of parasites included in the Cryptosporidium (Apicomplexa: Cryptosporidiidae) are described globally. Members of this genus occur within a broad spectrum of hosts – vertebrates, including humans. The outcome of Cryptosporidium infections involves not only globally significant economic losses at animal farms, but also a threat to public health.
The parasitology lab at SVI Prague has long-term specialisation in the diagnosis of members of the genus and further participates in activities such as describing new species and ranges of hosts, genetic diversity, dynamics of infection in clinically important species of Cryptosporidiium and possible preventive measures. Simultaneously, it is in the interest of the laboratory to continue in obtaining new, original results or supplementing existing ones, as has been the case in recent years during studies focusing on Cryptosporidium infections in large-scale bird farming. The genetic sequences of developmental stage isolates from spontaneous infections in various host species will also be used for mapping the current status in the Czech Republic.
Máca O., Pavlásek I. (2016) Cryptosporidium infections of ring-necked pheasants (Phasianus colchicus) from an intensive artificial breeding programme in the Czech Republic. Parasitol Res. 2016 May;115(5):1915-22. doi: 10.1007/s00436-016-4933-5. Epub 2016 Jan 27.
Máca O., Pavlásek I. (2015) First finding of spontaneous infections with Cryptosporidium baileyi and C. meleagridis in the red-legged partridge Alectoris rufa from an aviary in the Czech Republic. Vet Parasitol. 2015 Apr 30;209(3-4):164-8. doi: 10.1016/j.vetpar.2015.03.003. Epub 2015 Mar 14.